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. 2017 Sep 6;7:10585. doi: 10.1038/s41598-017-11115-1

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Two examples of gene neighbourhood analysis in Cyanobacteria. The taxonomic relationship of the eight Cyanobacteria species is depicted on the left, and the taxonomic levels are denoted on the top. Two gene clusters identified by gene neighbourhood analysis are on the right. Gene cluster 1 is conserved in the Order of Nostocales, and gene cluster 2 is species-specific. Annotations of these genes are shown on the bottom.