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. 2017 Sep 6;7:10585. doi: 10.1038/s41598-017-11115-1

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Comparison of the repeat number and the tetrad number distributions between HR WD40 and all WD40 proteins. In each panel, the red bars represent the data from HR WD40 proteins, while the blue bars denote the data from all WD40 proteins. (a) The distributions of the repeat numbers. (b) The distributions of the tetrad hydrogen bond networks numbers. (c) The distributions of tetrad densities (measured by the ratio of the tetrad number to the repeat number).