Table 1.
General data and characteristics of all subjects
| Control (n = 24) | Obese (n = 22) | Lean CRC (n = 36) | Obese CRC (n = 34) | |
|---|---|---|---|---|
| Gender | ||||
| Male, n (%) | 13 (54%) | 14 (64%) | 20 (56%) | 19 (56%) |
| Female, n (%) | 11 (46%) | 8 (36%) | 16 (44%) | 15 (44%) |
| Age (years) | 49.6 ± 6.9 | 48.8 ± 8.6 | 51.4 ± 13.5 | 51.1 ± 12.2 |
| BMI (kg/m2) | 22.9 ± 2.9 | 34.2 ± 3.1ax | 23.5 ± 1.9 | 32.8 ± 1.6ax |
| Lipid profile | ||||
| Triglycerides (mg/dl) | 92.8 ± 29 | 174 ± 30ax | 111.5 ± 34.5 | 179.4 ± 49.2ax |
| Total cholesterol (mg/dl) | 214 ± 28.5 | 323 ± 67.6ay | 248.8 ± 60.9 | 290.3 ± 80bz |
| LDL-cholesterol (mg/dl) | 129.8 ± 19.5 | 224.8 ± 42.5ax | 160.4 ± 39.3 | 208.8.3 ± 74.4ay |
Gender data were compared using Chi square (X 2) test. One way ANOVA and Tukey’s multiple comparisons test were used to analyze the rest of the data.
aSignificantly different from control at P < 0.0001, bSignificantly different from control at P < 0.001.
xSignificantly different from lean CRC patients at P < 0.0001, ySignificantly different from lean CRC patients at P < 0.001.
zSignificantly different from lean CRC patients at P < 0.05.
CRC: colorectal cancer, LDL: low density lipoprotein.