Table 2.
Best response (BR) and Clinical Benefit (CB) by fasting glucose and BMI1 at the time of BR assessment (N:102).
| Best Response | |||
|---|---|---|---|
| No PD2 | PD2 | Mann-Whitney | |
| N = 76 | N = 26 | ||
| Mean* ± SD | Mean* ± SD | p-value | |
| Fasting glucose at BR | 108.9 ± 29.3 | 122.6 ± 38.0 | <0.001 |
| BMI at BR | 26.9 ± 5.3 | 26.1 ± 6.4 | 0.052 |
| Clinical Benefit | |||
| Yes | No | Student’s T | |
| N = 41 | N = 41 | ||
| Mean* ± SD | Mean* ± SD | p-value | |
| Fasting glucose at BR | 108.2 ± 29.5 | 120.5 ± 33.0 | <0.001 |
| BMI at BR | 26.8 ± 5.4 | 26.9 ± 5.4 | 0.895 |
1BMI: body mass index.
2PD: Disease Progression.
*Mean weighted by number of cycles administered.