Table 2.
Modified diagnostic criteria for neurovascular compression of the cochlear nerve (NVC-C).
Consider diagnosis when paroxysmal, short-lasting tinnitus observed. |
a. Staccato character (tapping, clicking, or crackling in nature) |
b. Typically, unilateral, but bilateral involvement can also be seen. |
1. Responsiveness to low-dose carbamazepine (200–400 mg/day) |
a. Prompt tinnitus improvement (within 2 weeks) |
b. When the medication is stopped, the symptoms may recur. |
2. Associated ipsilateral symptoms |
a. Paroxysmal vertiginous spells |
b. Hemifacial spasms |
3. Supportive criteria – positive auditory evoked potential using Moller’s criteria41 |
a. Commonly normal before 2 years of symptoms |
b. Ipsilateral interpeak latency I-III ≥ 2.3 ms |
c. Reduced peak II amplitude <33% |
4. Exclusionary criteria for NVC-C |
a. Tumor of the cerebellopontine angle or internal auditory canal on MRI |
b. Demyelination disease on cerebral MRI |
5. Positive MRI for vascular conflict have no diagnostic specificity. |