Table 3. Summary of DNA bending angles induced by MBD2 binding.
| DNA | MBD2MBD+IDR | MBD2MBD | |||
|---|---|---|---|---|---|
| Bending angle (°) | N | Bending angle (°) | N | ||
| Unmethylated | CpG-free | 36.7°±27.6° | 91 | 39.2°±13.7° | 77 |
| CpG-rich | 66.4°±32.4° | 167 | 68.8°±30.7° | 102 | |
| CpG free region | 42.5°±26.3° | 113 | 48.9°±20.1° | 57 | |
| CpG rich region | 74.1°±35.7° | 76 | 69.9°±36.1° | 56 | |
| Methylated | CpG-free | N.A. | N.A. | ||
| CpG-rich | 103.5°±23.1° | 162 | 69.0°±32.6° | 182 | |
| CpG free region | 42.1°±38.1° | 105 | 41.4°±23.3° | 181 | |
| CpG rich region | 102.2°±41.3° | 73 | 62.6°±27.6° | 114 | |
The values represent mean ± SD from two to three experiments for each data set. The significance values regarding the difference among the data sets are reported in Supplementary Figure S8.