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. 2017 May 30;45(15):8806–8821. doi: 10.1093/nar/gkx491

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© The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 3. — Significant overlap between the Mediator binding sites and the locations of the CID boundaries. (A) Overview of the locations of CID boundaries (gray lines) and Mediator binding sites that overlap (red lines) or do not overlap (blue lines) with a CID boundary along the 16 yeast chromosomes. (B) Magnified 200 kb region from chrXVI (675 000–875 000), with Micro-C contact frequency represented as a heat map, the locations of previously reported CID boundaries (4) shown by vertical red lines, and the binding profiles of the tagged Mediator subunits shown in blue. The majority of the Mediator peaks are located at CID boundaries.