Table 1.
Effects of bovine serum albumin (BSA) treatment and iron-restricted diet (IRD) on body weight, kidney weight, kidney iron content, red blood cell count, haemoglobin, haematocrit, mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), and mean corpuscular haemoglobin concentration (MCHC) in mice.
| Vehicle | BSA | BSA + IRD | |
|---|---|---|---|
| Body weight (g) | 23.4 ± 1.1 | 23.7 ± 1.7 | 24 ± 2 |
| Right kidney weight (mg) | 109 ± 7 | 131 ± 18** | 129 ± 10** |
| Right kidney weight to body weight ratio | 4.6 ± 0.2 | 5.5 ± 0.5** | 5.4 ± 0.2* |
| Renal iron content (µg/g tissue) | 9.9 ± 3.6 | 9.7 ± 3 | 5.4 ± 1.9*# |
| Red blood cell (×104/µL) | 827 ± 63 | 829 ± 48 | 760 ± 49*# |
| Haemoglobin (g/dL) | 12.6 ± 1 | 12.4 ± 0.7 | 10.6 ± 1.1**## |
| Haematocrit (%) | 38.1 ± 3.3 | 38.1 ± 2 | 32.1 ± 3.1**## |
| MCV (fL) | 46.1 ± 1 | 45.8 ± 1.1 | 42.4 ± 1.6**## |
| MCH (pg) | 15.2 ± 3.3 | 15 ± 0.2 | 14 ± 0.6**## |
| MCHC (g/dL) | 33 ± 0.7 | 32.6 ± 0.4 | 33.3 ± 0.4# |
Data represent mean ± SD; n = 8 or 9; *P < 0.05, **P < 0.01 vs. control mice; # P < 0.05, ## P < 0.01 vs. BSA-treated mice.