Table 2.

Effects of bovine serum albumin (BSA) treatment and iron-restricted diet (IRD) on the levels of plasma total protein, plasma albumin, blood urea nitrogen (BUN), plasma creatinine, plasma ferritin, plasma iron, transferrin saturation (TSAT), and plasma hepcidin-1 in mice.

	Vehicle	BSA	BSA + IRD
Plasma total protein (g/dL)	6.3 ± 1.2	9.2 ± 1.1**	9.2 ± 0.9**
Plasma albumin (g/dL)	2.8 ± 0.4	5.8 ± 0.9**	5.6 ± 1.1**
BUN (mg/dL)	29.2 ± 5.0	40.0 ± 9.8**	32.4 ± 5.7#
Plasma creatinine (mg/dL)	0.61 ± 0.08	0.61 ± 0.09	0.59 ± 0.09
Plasma ferritin (ng/mL)	814.2 ± 178.6	631.8 ± 170.0	323.2 ± 145.91**##
Plasma iron (µg/dL)	60.0 ± 7.3	78.2 ± 9.6**	61.9 ± 12.1##
TSAT (%)	25.1 ± 5.74	38.5 ± 6.8**	25.8 ± 8.3##
Plasma hepcidin-1 (ng/dL)	51.0 ± 33.8	112.6 ± 30.8**	0.4 ± 0.11*##

Data represent mean ± SD; n = 5–13; *P < 0.05, **P < 0.01 vs. control mice; ^# P < 0.05, ^## P < 0.01 vs. BSA-treated mice.