Table 3. Top 10 miRNAs returned from analyses of Hippo effectors with neural crest gene sets.

Hippo effectors plus neural plate border
miRNA	Group	Score	Combination
hsa-miR-8085	10	4.613	AJUBA, DLX6, MSX2, SMAD2, SMAD3, TEAD1, TFAP2A, TP73, WWTR1, ZIC1
hsa-miR-550a-5p	10	4.079	AJUBA, FOXI1, MSX2, PAX3, SMAD2, SMAD3, SMAD4, TP73, WWTR1, YAP1
hsa-miR-6760–5p	9	3.745	AJUBA, DLX6, MSX2, SMAD3, TEAD1, TFAP2A, TP73, YAP1, ZIC1
hsa-miR-7113–5p	8	3.481	MSX2, PAX7, SMAD3, SMAD4, TEAD1, TEAD2, TFAP2A, YAP1
hsa-miR-3183	10	3.430	AJUBA, MSX1, MSX2, PAX7, SMAD2, SMAD3, SMAD4, TEAD1, TP73, ZIC1
hsa-miR-550a-3–5p	9	3.386	AJUBA, MSX2, PAX3, SMAD2, SMAD3, SMAD4, TP73, WWTR1, YAP1
hsa-miR-203b-3p	9	3.301	AJUBA, MSX1, PAX3, SMAD2, SMAD4, TFAP2A, TP73, YAP1, ZIC1
hsa-miR-193a-3p	9	3.300	AJUBA, HES1, PAX7, SMAD2, SMAD4, TEAD1, WWTR1, YAP1, ZIC5
hsa-miR-193b-3p	9	3.195	AJUBA, HES1, MSX2,PAX7,SMAD2,SMAD3,WWTR1,YAP1,ZIC5
hsa-miR-4715–5p	8	3.156	AJUBA,HES1,PAX7,SMAD2,SMAD3,WWTR1,ZIC1,ZIC5
Hippo Effectors plus Epithelial-to-Mesenchymal Transition
miRNA	Group	Score	Combination
hsa-miR-636	10	4.255	AJUBA, LMO4, SNAI1, SNAI2, SOX5, SOX9, TEAD1, TWIST1, TWIST2, YAP1
hsa-miR-4660	11	3.611	FOXD3, LMO4, SNAI2, SOX10, SOX5, SOX8, SOX9, TEAD1, TP73, YAP1, ZEB2
hsa-miR-4313	9	3.469	SNAI1, SOX10, SOX8, TEAD1, TP73, TWIST1, TWIST2, YAP1, ZEB2
hsa-miR-548aq-3p	11	3.386	LMO4, RHOB, SNAI2, SOX10, SOX5, TEAD1, TP73, TWIST1, WWTR1, YAP1, ZEB2
hsa-miR-1273h-5p	9	3.168	AJUBA, LMO4, RHOB, SOX10, SOX5, SOX9, TEAD1, TP73, ZEB2
hsa-miR-138–5p	10	2.949	AJUBA, FOXD3, SOX5, SOX8, SOX9, TEAD1, TEAD2, TP73, YAP1, ZEB2
hsa-miR-6797–5p	9	2.940	AJUBA, RHOB, SNAI1, SOX10, SOX5, SOX8, SOX9,TEAD2, TP73
hsa-miR-141–3p	9	2.926	LMO4, SOX5, SOX9, TEAD1, TP73, TWIST2, WWTR1, YAP1, ZEB2
hsa-miR-6738–5p	7	2.779	RHOB, SNAI1, SOX10, SOX8, TEAD1, TEAD2, TP73
hsa-miR-361–3p	9	2.766	AJUBA, FOXD3, LMO4, RHOB, SNAI1, SOX8, TEAD2, TP73, YAP1