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Re-equilibration of G-quadruplex sequence 35 after temperature jump. (A) BEST-TROSY HSQC spectra (88 s time resolution) after heat shock, after 2.5 and 5 h. Assignments are indicated. (B) Decay and build-up curves of form 1 and form 2 for G10 and G17 giving a re-equilibration constant of ∼0.012 min−1. For details of the fitting procedure see the supporting information.
