Table 1.
Design and patient characteristics for studies included in the meta-analysis.
| Source | Sample size (Intensive/Standard) | Hematoma volume (ml) (Intensive/Standard) | Sex (male) | Mean age (year) | Duration of fellow-up (month) | Baseline BP (mmHg) (Intensive/Standard) | BP target in intensive group (mmHg) | BP target in standard group (mmHg) | Outcomes | Country | Jadad score |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Anderson et al., 2008 | 203/201 | 14.2 ± 14.5/12.7 ± 11.6 | 64.9% | 62.5 | 3 | SBP: 180/182 | SBP < 140 | SBP < 180 | Death or dependency, mRS, NIHSS, Barthel index, AE | Australia | 4 |
| Anderson et al., 2013 | 1403/1436 | 11/11 | 62.9% | 63.5 | 3 | SBP: 179/179 | SBP < 140 | SBP < 180 | Death or dependency, mRS, AE, quality of life | Australia | 5 |
| Butcher et al., 2013 | 39/36 | 25.6 ± 30.84/26.9 ± 25.24 | 72% | 69.7 | 3 | SBP: 182/184 | SBP < 150 | SBP: 150–180 | Mortality, mRS, Barthel Index | Canada | 3 |
| Koch et al., 2008 | 21/21 | 12.5 ± 17.2/8.5 ± 9.8 | 54.8% | 60.6 | 3 | MAP: 144/151 | MAP < 110 | MAP: 110–130 | Mortality, mRS | USA | 3 |
| Potter et al., 2009 | 18/7 | — | 55.2% | 74 | 3 | SBP: 182/181 | SBP: 145–155 | SBP > 155 | Dead or dependent, mRS, AE | UK | 3 |
| Qureshi et al., 2016 | 500/500 | 10.3/10.2 | 62% | 61.9 | 3 | SBP: 200/201 | SBP: 110–139 | SBP: 140–179 | Death or dependency, mRS, AE, EQ-5D, NIHSS | USA | 5 |
Abbreviations: AE: adverse event; mRS: Modified Rankin Scale; NIHSS: National Institute of Health stroke scale; BP: blood pressure; SBP: systolic blood pressure; MAP: mean arterial pressure; EQ-5D: European Quality of Life-5Dimensions.