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In vitro pigment inhibition by compound NP16. (A) Inhibition of wild-type (WT) S. aureus pigmentation in the presence of increasing concentrations of NP16. (B) Pigment inhibition by NP16; the IC50 for pigment formation is ∼300 nM. (C) The chemical structure of compound NP16. (D) Growth curve of S. aureus COL in the presence of different concentrations of NP16. All data represent mean values ± SD.
