FIG 6 .
NP16 treatment leads to increased sensitivity to oxidation and neutrophil killing. (A) Cytotoxic activity of compound NP16 on different cell lines. (B) UV spectrum of carotenoids extracted from different strains, with or without NP16 treatment. (C) Increased susceptibility of the NP16-treated S. aureus COL strain to killing by hydrogen peroxide. (D) Increased susceptibility of the NP16-treated S. aureus COL strain to killing by neutrophils. All data represent mean values ± SD. ns, not significant; *, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, P < 0.0001. P values were determined using GraphPad Prism with an unpaired parametric t test and Welch’s correction.