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Effect of baicalin on glial cell activation in vitro. (a) Baicalin dose dependently inhibited the secretion of proinflammatory cytokines IL-1β and IL-6, which were determined by ELISA. N = 6 in each group, ∗∗∗∗ represents p < 0.0001, and ∗∗∗ represents p < 0.0005. (b) Immunoblot analyses of p65 from nuclear fraction along with loading control histone H3. ∗∗ represents p < 0.005.
