Table 14.

Effect of NAC on blood DC levels in women with LLABCs.

Pathological responders	DC baseline levels (%)
	p value
GPRs + PPRs	1.34 ± 0.30
GPRs + PPRs versus HFDs	NS
GPRs	1.64 ± 0.25
GPRs versus HFD	NS
PPRs	1.29 ± 0.25
PPRs versus HFDs	NS
Pathological responders	DC post-NAC levels (%)
	p value
GPRs	3.24 ± 1.62
GPRs versus HFDs	0.024∗
PPRs	2.17 ± 0.5
PPRs versus HFDs	NS

NAC: neoadjuvant chemotherapy; LLABCs: large and locally advanced breast cancers; GPRs: good pathological responders (pCR or ≥90% reduction of invasive disease); PPRs: poor pathological responders (no response or <90% reduction of invasive disease); HFDs: healthy female donors; NS: nonsignificant; ^∗statistically significant.