Table 5.

Analyses of tumour-infiltrating CD1a⁺ dendritic cells and CD66b⁺ neutrophils in the breast tumours in women with LLABCs and subsequent PCR following NAC.

Cell subsets	Groups	Pre-NAC intratumoural median (range)(3)	p value(3) (GPR versus PRR, PCR versus non-PCR)	Pre-NAC peritumoural median (range)(3)	p value(4) (GPR versus PRR, PCR versus non-PCR)
CD1a+ (n = 16)	Good pathological response (GPR, n = 9)	3 (1–104)	0.837	1 (1–16)	0.837
	Poor pathological response (PPR, n = 7)	11 (0–63)		2 (0–11)
	Pathological complete response (PCR, n = 6)	3 (1–104)	0.713	1.5 (1–16)	0.492
	Nonpathological complete response (non-PCR, n = 10)	4 (0–63)		1.5 (0–11)
CD66b+ (n = 16)	Good pathological response (GPR, n = 9)	2 (0–53)	0.174	2 (0–71)	0.408
	Poor pathological response (PPR, n = 7)	1 (0–3)		1 (0–2)
	Pathological complete response (PCR, n = 6)	3 (0–53)	0.181	5 (0–71)	0.118
	Nonpathological complete response (non-PCR, n = 10)	1 (0–3)		1 (0–2)

LLABCs: large and locally advanced breast cancers; NAC: neoadjuvant chemotherapy; ⁽³⁾total cell count per 5 high-power fields (core biopsies of breast cancers); ⁽⁴⁾Mann–Whitney U test.