Table 6.
Alteration of tumour-infiltrating CD1a+ dendritic cells and CD66b+ neutrophils in breast tumours in women with LLABCs undergoing NAC.
| Groups | Pre-NAC median (range)(3) | Post-NAC median (range)(3) | p value(4) (pre- versus post-NAC) | |
|---|---|---|---|---|
| CD1a+ | Intratumoural infiltration (n = 16) | 3.5 (0–104) | 0 (0–2) | 0.001∗ |
| Peritumoural infiltration (n = 16) | 1.5 (0–16) | 1 (0–7) | 0.184 | |
|
| ||||
| CD66b+ | Intratumoural infiltration (n = 16) | 1 (0–53) | 4.5 (0–50) | 0.125 |
| Peritumoural infiltration (n = 16) | 1.5 (0–71) | 2.5 (0–82) | 0.470 | |
LLABCs: large and locally advanced breast cancers; NAC: neoadjuvant chemotherapy; (3)cell count in 400x HPF; (4)Wilcoxon signed-rank test; ∗statistically significant.