Figure 2.
Overexpression of miR-184 inhibits CRC cell proliferation, migration and invasion. (A) The reverse transcription-quantitative polymerase chain reaction was performed to detect the expression level of miR-184 in HCT116 and SW620 cells following transfection with miR-184 mimic or NC, respectively. (B) Cell proliferation was determined using an MTT assay in HCT116 and SW620 cells following transfection with miR-184 mimic or NC. Overexpression of miR-184 was identified top inhibit cell proliferation in HCT116 and SW620 cells. (C) Cell migration and invasion was determined using a Transwell assay in HCT116 and SW620 cells following transfection with miR-184 mimic or NC. Upregulation of miR-184 suppressed CRC cell migration and invasion compared with NC-transfected cells. *P<0.05 vs. NC. miR-184, microRNA-184; CRC, colorectal cancer; NC, negative control.