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. 2017 Jul 8;14(3):3255–3260. doi: 10.3892/ol.2017.6561

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Figure 5. — miR-346 promotes the proliferation, migration, and invasion of liver cancer cells via FBXL2. CCK-8 assay (A), Transwell-migration assay (B), Transwell-invasion assay (C) were performed to evaluate the reversal by FBXL2 siRNA of miR-346 inhibitors induced inhibition of cell proliferation, migration, and invasion in MHCC-97H cells. CCK-8 assay (D), Transwell-migration assay (E), Transwell-invasion assay (F) were performed to evaluate the reversal by FBXL2 overexpression of miR-346 mimics induced increase of cell proliferation, migration, and invasion in HepG2 cells. All data are shown as mean ± SD from three independent experiments. **P<0.01.