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COLO320 cell clonogenic survival, LDH release and intracellular ROS are cell density-dependent when exposed to oxaliplatin (0–125 µM, 24 h). (A) COLO320 cell clonogenic survival at low and high cell density. (B) LDH release of COLO320 cells at low and high cell density. (C) Intracellular ROS of COLO320 cells at low and high cell density. n=4–7; *P<0.05, compared with high-density cell group. LDH, lactate dehydrogenase; ROS, reactive oxygen species.
