Table II.
Univariate and multivariate analysis of the association of prognostic factors in esophageal squamous cell carcinoma with overall survival.
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| Characteristic | RR | P-value | 95% Cl | RR | P-value | 95% Cl |
| Sex | ||||||
| Male vs. female | 1.794 | 0.138 | 0.828–3.887 | |||
| Age, years | ||||||
| ≤60 vs. >60 | 0.821 | 0.531 | 0.443–1.522 | |||
| Smoking | ||||||
| No vs. yes | 1.237 | 0.497 | 0.670–2.287 | |||
| Alcohol | ||||||
| No vs. yes | 1.446 | 0.296 | 0.724–2.887 | |||
| Tumor size, cm | ||||||
| ≤3 vs. >3 | 2.058 | 0.041a | 1.029–4.114 | 1.322 | 0.449 | 0.642–2.721 |
| pT | ||||||
| T1 and T2 vs. T3 | 1.493 | 0.102 | 0.924–2.414 | |||
| Pathological grade | ||||||
| II and II vs. III | 1.344 | 0.267 | 0.797–2.264 | |||
| Lymph node metastasis | ||||||
| No vs. yes | 5.76 | 0.001a | 3.043–10.905 | 4.256 | 0.001a | 2.161–8.380 |
| MAGE-A9 | ||||||
| High vs. low | 4.067 | 0.001a | 1.932–8.560 | 2.93 | 0.006a | 1.367–6.277 |
a
P<0.05. MAGE-A9, melanoma-associated antigen-9; pT, pathological tumor stage; RR, relative risk; CI, confidence interval.