Table IV.
Frequency of LAPTM4B in female PTC patients and healthy controls.
| LAPTM4B status | Healthy controls, n (%) n=249 | PTC, n (%) n=132 | Odds ratio (95% CI) | P-value |
|---|---|---|---|---|
| Allele | ||||
| *1 | 395 (79.3) | 177 (67.0) | ||
| *2 | 103 (20.7) | 87 (33.0) | 1.968 (1.363–2.841) | <0.001a |
| Genotype | ||||
| *1/1 | 156 (62.7) | 64 (48.5) | ||
| *1/2 | 83 (33.3) | 49 (37.1) | 1.443 (0.880–2.365) | 0.146b |
| *2/2 | 10 (4.0) | 19 (14.4) | 5.494 (2.198–13.730) | <0.001b |
a
Compared with LAPTM4B*1.
b
Compared with LAPTM4B*1/1. LAPTM4B, lysosome-associated protein transmembrane 4-β; PTC, papillary thyroid carcinoma; CI, confidence interval.