Figure 5.

FOXM1 siRNA suppressed the viability, migration and invasion of HeLa and SiHa cells. (A) Western blot analysis of FOXM1 protein expression in HeLa and SiHa cells following transfection with the FOXM1 siRNA. β-actin was used as a loading control. (B) An MTT assay demonstrated that FOXM1 siRNA suppressed the cellular viability in HeLa and SiHa cells, compared with that in control groups. (C) Transwell migration and invasion assays identified that FOXM1 siRNA significantly decreased the cell migratory and invasive capabilities of HeLa and SiHa cells. *P<0.05, vs. respective controls. FOXM1, forkhead box M1; siRNA, short interfering RNA.