Table II.

Correlation between inflammatory cell infiltration in the invasive front and main mass of primary tumor and morphological variables of colorectal cancer.

		Inflammatory cell infiltration in the invasive front of tumor		Inflammatory cell infiltration in the center of tumor mass
Variables	N 160	R	P-value	R	P-value
Venous invasion
Absent	113	-0.193	0.020	NS	NS
Present	46
Lymphatic invasion
Absent	121	-0.173	0.038	NS	NS
Present	38
Perineural invasion
Absent	143	NS	NS	-0.191	0.022
Present	17
No. of removed lymph nodes
<5	13	NS	NS	NS	NS
5–10	29
>10	116
Lymph node metastasis
Absent	81	NS	NS	-0.230	0.005
Present	79
Type of lymph node metastasis
Micro	27	NS	NS	-0.198	0.017
Macro	52
Number of metastatic lymph nodes
<5	49	NS	NS	-0.323	0.012
>5	26
Lymph node pouch invasion
Absent	11	-0.212	0.010	-0.191	0.021
Present	68
Distant metastasis
Absent	143	NS	NS	NS	NS
Present	17
Distant metastasis size (mm)
<10	11	NS	NS	NS	NS
>10	6
Tumor deposits
Absent	133	NS	NS	NS	NS
Present	27
Size of tumor deposits (mm)
<2.5	10	NS	NS	NS	NS
>2.5	17
TSP (%)
<50	94	-0.212	0.015	NS	NS
>50	66
Tumor budding
Absent	94	NS	NS	NS	NS
Present	66
Crohn's-like aggregates of lymphocyte
Absent	113	NS	NS	0.195	0.019
Present	42
Necrosis
Absent	45	NS	NS	NS	NS
Focal	61
Moderate	36
Extensive	18
Fibrosis
Absent	11	-0.293	0.000	NS	NS
Focal	72
Moderate	43
Extensive	34
Maturation of fibrotic stroma
Immature	12	0.238	0.004	0.256	0.002
Intermediate	91
Mature	57

Bold numbers indicate values considered to be statistically significant. Spearman's correlation coefficient test; NS, not statistically significant; TSP, tumor stroma percentage.