Figure 1.

Expression of CD147 in human urothelial cancer cell lines. (A) Western blot analysis of CD147 expression in human and mouse urothelial cell lines. Human normal bladder urothelial cells (HUC) and various bladder cancer cell lines were examined. β-actin was used as a loading control (B) Correlation analysis between the expression of CD147 and the hTERT promoter-driving activity in human urothelial cells. The band density in was determined by a densitometric analysis. The hTERT promoter-driving activity was measured as an index of malignancy using an hTERT promoter-dependent expression system. CD147, cluster of differentiation 147; hTERT, human telomerase reverse transcriptase; a.u., arbitrary unit.