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. 2017 Jun 27;14(3):2709–2714. doi: 10.3892/ol.2017.6482

Figure 5.

Figure 5.

RA enhances the effects of TMZ on Keap1/Nrf2/ARE signaling. (A) Keap1/Nrf2/ARE mRNA levels detected by RT-PCR. (B) Protein levels were detected using western blot analysis. Bar charts show relative protein levels in the treatment and control groups. Statistically significant difference (*P<0.05, **P<0.01) between the TMZ group and the control group. Statistically significant difference (#P<0.05, ##P<0.01) between TMZ group and RA+TMZ group. RA, retinoic acid; TMZ, temozolomide.