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. 2017 Jul 10;14(3):2743–2748. doi: 10.3892/ol.2017.6567

Table III.

Univariate and multivariate analyses of overall survival of patients with NCSLC.

Univariate analysis Multivariate analysis


Variable HR 95% CI P-value HR 95% CI P-value
Sex (male vs. female) 0.948 0.660–1.362 0.772 0.968 0.643–1.456 0.875
Age (≤60 vs. >60) 1.159 0.810–1.658 0.419 1.216 0.996–2.681 0.303
Histologic type (adenocarcinoma vs. squamous cell carcinoma) 0.855 0.477–1.529 0.597 1.099 0.574–2.105 0.776
Tumor differentiation (well vs. moderate vs. poor) 0.862 0.462–1.548 0.829 1.289 0.656–1.857 0.721
Tumor size (T1 vs. T2 vs. T3 vs. T4) 1.976 0.425–4.088 0.046a 0.802 0.117–4.740 0.379
Lymph node metastasis (absent vs. present) 1.261 0.441–1.192 0.365 1.543 0.619–3.848 0.352
Lung cancer stages (1 vs. 2 vs. 3) 1.344 1.072–2.466 0.032a 1.815 1.347–2.802 0.041a
SPOP expression (low vs. high) 0.652 0.306–0.861 0.039a 0.634 0.422–0.712 0.045a
a

Statistically significant. HR, hazard ratio; CI, confidence interval; SPOP, speckle-type POZ domain protein.