Table IV.

Univariate and multivariate analyses of various clinical variables in gastric cancer patients based on OS

	Univariate analysis		Multivariate analysis
Clinical variables	HR (95% CI)	P-value	HR (95% CI)	P-value
Age (<60 vs. ≥60 years)	1.100 (0.561–2.157)	0.782	1.259 (0.604–2.625)	0.540
Sex (male vs. female)	1.611 (0.854–3.040)	0.141	0.681 (0.337–1.377)	0.258
Tumor size (≤5 vs. >5 cm)	0.621 (0.333–1.158)	0.134	0.690 (0.336–1.300)	0.251
Grade (G1+G2 vs. G3)	2.420 (1.205–4.857)	0.013	0.651 (0.299–1.267)	0.243
Clinical stage (I+II vs. III+IV)	6.771 (2.833–16.18)	<0.001	0.173 (0.071–0.417)	<0.001
CEA (N vs. P)	0.503 (0.266–0.948)	0.034	1.144 (0.544–2.405)	0.723
CA199 (N vs. P)	3.297 (1.694–6.419)	<0.001	0.412 (0.209–0.811)	0.010
CA125 (N vs. P)	1.976 (0.772–5.060)	0.156	0.853 (0.308–2.364)	0.760
CA724 (N vs. P)	2.013 (1.081–3.748)	0.027	0.601 (0.321–1.125)	0.112
sMR (low vs. high)	2.803 (1.335–5.886)	0.006	0.604 (0.273–1.336)	0.213
sCD163 (low vs. high)	3.759 (1.827–7.734)	<0.001	0.667 (0.280–1.584)	0.359

HR, hazard ratio; CI, confidence interval; N, negative; P, positive.