Table 4.
Results: lesion progression in test and control groups and RR (95s% CI) for caries progression
| Progression differences between test and control or placebo treatment < groups | |||
| At 12 months | Ekstrand | ||
| PWC | p < 0.001 | et al. [13] | |
| RI s+ FV | 23.1s% | ||
| FV | 61.5s% | ||
| ICDAS score | p = 0.002 | ||
| RI s+ FV | 31s% | ||
| FV | 66.7s% | ||
| At 36 months | Martignon | ||
| PWC | et al. [14] | ||
| RI | 32s% | ||
| Sealants | 41s% | ||
| Microbrush | 70s% | ||
| RI vs. microbrush | p = 0.0012 | ||
| Sealant vs. microbrush | p = 0.0291 | ||
| At 18 months | Paris et al. | ||
| PWC | p = 0.063 | [15] | |
| RI | 3.7s% | Meyer- | |
| Water | 22.2s% | Lueckel et | |
| DSR | p = 0.021 | al. [16] | |
| RI | 7s% | ||
| Water | 37s% | ||
| At 36 months | Paris et al. | ||
| PWC | p = 0.008 | [15] | |
| RI | 4s% | Meyer- | |
| Water | 35s% | Lueckel et | |
| DSR | p = 0.002 | al. [16] | |
| RI | 4s% | ||
| Water | 42s% | ||
| RR for caries progression in the test group(s) compared with the control group (95s% CI) | |||
| At 12 months | Ekstrand | ||
| PWC | et al. [13] | ||
| RI s+ FV vs. FV | 0.38 (0.2 – 0.7) | ||
| ICDAS score | |||
| RI s+ FV vs. FV | 0.46 (0.28 – 0.77) | ||
| At 36 months | Martignon | ||
| PWC | et al. [14] | ||
| RI vs. microbrush | 0.46 (0.28 – 0.77) | ||
| Sealant vs. microbrush | 0.58 (0.37 – 0.9) | ||
| RI vs. sealant | 0.8 (0.44 – 1.47) | ||
| At 18 months | Paris et al. | ||
| PWC | [15] | ||
| RI vs. water | 0.17 (0.02 – 1.29) | Meyer- | |
| DSR | Lueckel et al. | ||
| RI vs. water | 0.2 (0.05 – 0.83) | [16] | |
| At 36 months | Paris et al. | ||
| PWC | [15] | ||
| RI vs. water | 0.11 (0.01 – 0.82) | Meyer- | |
| DSR | Lueckel et | ||
| RI vs. water | 0.09 (0.01 – 0.65) | al. [16] | |
DSR = Digital subtraction radiography; ICDAS = International Caries Detection and Assessment System; PWC = pair-wise comparison.