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. 2015 Aug 1;24(6):565–570. doi: 10.1159/000435955

Table 3.

Sensitivity, specificity, predictive values, likelihood ratios, and OR for the optimal cutoff for the number of medications prescribed for predicting risk of PIM according to the STOPP and Beers 2012 criteria

Cutoff ≥6 drugsa PIM group, n/total (%) Non-PIM group, n/total (%) Sen, % (95% CI) Spe, % (95% CI) PPV, % (95% CI) NPV, % (95% CI) PLR (95% CI) NLR (95% CI) Adjusted OR (95% CI) p
STOPP criteria 74/94 (78.7) 29/47 (61.7) 79 (69–87) 38 (25–54) 72 (62–80) 47 (31–64) 1.3 (1.0–1.6) 0.6 (0.3–0.9) 2.1 (1.1–5.0) b 0.034

Beers 2012 criteria 76/94 (80.9) 27/47 (57.4) 81 (71–88) 43 (28–58) 74 (64–82) 53 (36–69) 1.4 (1.1–1.8) 0.5 (0.3–0.8) 2.2 (1.3–6.6)c 0.012

NLR = Negative likelihood ratio; PLR = positive likelihood ratio; Sen = sensitivity; Spe = specificity.

a

Optimal cutoff value estimated using the Youden index.

b

Adjusted for age, sex and severity of comorbidities.

b

Adjusted for age, sex, severity of comorbidities and history of psychiatric disorders.