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. 2001 Sep 1;29(17):3621–3630. doi: 10.1093/nar/29.17.3621

Figure 1.

Figure 1

Homology of the Erb1/Bop1 primary structure in eukaryotes. Organisms and sequence accession nos are: Sce, S.cerevisiae (NP_013764); Spo, Schizosaccharomyces pombe (S54549); Ath, Arabidopsis thaliana (AAD25679); Cel, Caenorhabditis elegans (T26995); Dme, Drosophila melanogaster (T13579); Mmu, Mus musculus (NP_038509); Hsa, Homo sapiens (BAA09473, incomplete sequence). Initial alignment was obtained with ClustalX (34) and then manually edited using GeneDoc (35). Black shading indicates identical residues and conservative substitutions in all sequences; grey shading indicates such residues in >50% sequences. WD repeats 1–5 were identified by a search against the Pfam database (36) in all seven sequences. The WD1 repeat is the closest to the canonical WD40 structure (5). Numbers within parentheses in each sequence indicate lengths of small unique amino acid insertions and the N-terminal domains, which are not conserved at the primary structure level (see text).