Table 2.
C (n = 5) | D (n = 5) | DI (n = 5) | |
---|---|---|---|
Cinulin, mL/min/100 g | 0.47 ± 0.02 | 0.84 ± 0.1** | 0.6 ± 0.07 |
CPAH, mL/min/100 g | 1.34 ± 0.27 | 2.41 ± 0.43* | 1.72 ± 0.36 |
Cinulin/CPAH | 0.43 ± 0.06 | 0.38 ± 0.05 | 0.4 ± 0.07 |
Bwt0, g | 203.2 ± 5.6 | 196.2 ± 1.5 | 213.6 ± 4.4 |
MBP, mm Hg | 126.6 ± 3.3 | 123.9 ± 4.2 | 124.0 ± 6.5 |
V, mL/min | 0.011 ± 0.003 | 0.02 ± 0.003** | 0.02 ± 0.01 |
C = Controls; D = diabetic rats; DI = insulin-treated diabetic rats; Cinulin = clearance of insulin; CPAH = clearance of PAH; Bwt0 = initial body weight; MBP = mean blood pressure; V = urine flow rate during clearance experiments.
p < 0.05
p < 0.01 compared to controls.