Table 3.

Multivariate logistic regression analysis of demographic parameters predicting symptoms in lung cancer

Variables1	OR	95% CI	p
Pain
Gender (female)	1.402	0.929 − 2.115	0.107
Body weight	0.987	0.977 − 0.996	0.007
Disease stage	0.944	0.735 − 1.213	0.653
Weight loss	1.023	1.007 − 1.040	0.005
Metastasis	1.727	1.102 − 2.708	0.017
TST	0.986	0.977 − 0.994	0.001
Tiredness
Body weight	0.982	0.971 − 0.993	0.002
Disease stage	1.130	0.861 − 1.484	0.378
Weight loss	1.031	1.002 − 1.060	0.037
Metastasis	1.537	0.914 − 2.587	0.105
Drowsiness
Age	1.010	0.996 − 1.024	0.152
Body weight	0.997	0.987 − 1.006	0.524
Disease stage	1.032	0.803 − 1.326	0.807
Comorbidity	1.264	0.979 − 1.632	0.072
Weight loss	1.044	1.021 − 1.067	<0.0001
Metastasis	1.640	1.048 − 2.567	0.031
TST	0.990	0.987 − 0.998	0.020
Nausea
Age	0.985	0.972 − 0.997	0.017
Body weight	0.991	0.982 − 1.000	0.057
Disease stage	1.020	0.790 − 1.317	0.881
Weight loss	1.030	1.011 − 1.050	0.002
Metastasis	1.276	0.814 − 2.001	0.289
TST	0.986	0.977 − 0.995	0.004
Lack of appetite
Age	1.008	0.993 − 1.022	0.314
Body weight	0.970	0.960 − 0.980	<0.001
Disease stage	1.172	0.903 − 1.520	0.234
Comorbidity	1.463	1.114 − 1.921	0.006
Weight loss	1.046	1.022 − 1.072	<0.001
Metastasis	1.477	0.924 − 2.361	0.103
TST	0.987	0.972 − 0.991	<0.001
Shortness of breath
Age	1.005	0.991 − 1.019	0.502
Body weight	0.984	0.975 − 0.993	0.001
Comorbidity	1.903	1.462 − 2.477	<0.001
Depression
Gender (female)	1.777	1.210 − 2.610	0.003
Body weight	0.988	0.979 − 0.997	0.010
Disease stage	1.065	0.826 − 1.374	0.626
Comorbidity	1.421	1.116 − 1.809	0.004
Weight loss	1.042	1.021 − 1.063	<0.0001
Metastasis	1.353	0.863 − 2.119	0.187
TST	0.988	0.979 − 0.997	0.009
Anxiety
Age	1.010	0.996 − 1.023	0.167
Gender (female)	1.791	1.195 − 2.684	0.005
Body weight	0.991	0.982 − 1.001	0.071
Disease stage	1.088	0.846 − 1.401	0.511
Comorbidity	1.238	0.961 − 1.594	0.098
Weight loss	1.040	1.018 − 1.062	<0.0001
Metastasis	1.328	0.848 − 2.079	0.215
TST	0.992	0.983 − 1.001	0.077
Poor well-being
Age	1.028	1.013 − 1044	<0.0001
Body weight	0.981	0.971 − 0.991	<0.0001
Disease stage	0.998	0.770 − 1.294	0.990
Comorbidity	1.198	0.903 − 1.590	0.211
Weight loss	1.049	1.022 − 1.077	<0.0001
Metastasis	2.168	1.349 − 3.484	0.001
TST	0.991	0.982 − 1.000	0.044
Awakening
Gender (female)	1.361	0.936 − 1.979	0.107
Disease stage	1.403	1.080 − 1.822	0.011
Comorbidity	1.406	1.107 − 1.785	0.005
Weight loss	1.027	1.008 − 1.046	0.004
Metastasis	1.291	0.822 − 2.027	0.267

TST, time since diagnosis.

¹Only variables derived from predictive factors with a significance <0.05 in the univariate analysis were included.