Table 2.
Characteristics of cohorts L and V
| Cohort L | Cohort V | p value | |
|---|---|---|---|
| Demographics | |||
| Patients, n | 269 | 146 | |
| Age, years | 71.0 [55.5 – 78.0] | 70.0 [56.8 – 78.0] | 0.889 |
| Male/female sex | 146/123 (54.3/45.7) | 99/47 (67.8/32.2) | 0.009 |
| GFRea, ml/min/1.73 m2 | 60.5 [34.7 – 85.6] | 38.3 [17.1 – 81.2] | <0.001 |
| Ca2s+, mmol/l | 1.18 [1.08 – 1.25] | 1.13 [1.06 – 1.21] | 0.003 |
| CaTot, mmol/l | 2.07 [1.87 – 2.27] | 2.07 [1.92 – 2.20] | 0.917 |
| Type of patient medical/surgical/trauma | 191/73/5 (71.0/27.1/1.9) | 107/34/5 (73.3/23.3/3.4) | 0.450 |
| Critically ill patientsb | 36 (13.4) | 12 (8.2) | 0.148 |
| Comorbidities | |||
| Hypertension | 151 (56.1) | 106 (72.6) | 0.001 |
| Neoplasm | 122 (45.4) | 47 (32.2) | 0.012 |
| Acute renal impairment moderate/severe | 75/56 (27.9/20.8) | 33/66 (22.6/45.2) | <0.001 |
| Diabetes mellitus | 63 (23.4) | 64 (43.8) | <0.001 |
| Dyslipidemia | 61 (22.7) | 53 (36.3) | 0.04 |
| Chronic renal impairment | 54 (20.1) | 81 (55.5) | <0.001 |
| Chronic liver disease | 42 (15.6) | 22 (15.1) | 1.00 |
| Chronic obstructive pulmonary disease | 40 (14.9) | 30 (20.5) | 0.170 |
| Chronic heart failure | 33 (12.3) | 26 (17.8) | 0.141 |
| Chronic alcoholism | 26 (9.7) | 16 (11.0) | 0.734 |
| Bone diseases | 22 (8.2) | 10 (6.8) | 0.703 |
| Hypothyroidism/hyperthyroidism | 19/2 (7.1/0.7) | 7/10 (4.8/6.8) | 0.001 |
| Hypoparathyroidism/hyperparathyroidism | 1/25 (0.4/9.3) | 32/7 (21.9/4.8) | <0.001 |
| Initial department of admission | |||
| General surgery | 53 (19.7) | 17 (11.6) | 0.040 |
| Medical oncology | 34 (12.6) | 2 (1.4) | <0.001 |
| Internal medicine | 24 (8.9) | 3 (2.1) | 0.006 |
| Nephrology | 24 (8.9) | 70 (47.9) | <0.001 |
| Gastroenterology | 18 (6.7) | 10 (6.8) | 1.000 |
| Hematology | 15 (5.6) | 2 (1.4) | 0.040 |
| Intensive care unit | 12 (4.5) | 13 (8.9) | 0.084 |
| Other departments | 89 (33.1) | 29 (19.9) | – |
| Outcomes | |||
| Length of stay, days | 18.0 [10.0 – 34.0] | 16.0 [8.0 – 31.5] | 0.204 |
| Mortality | 60 (22.3) | 14 (9.6) | 0.001 |
Values are expressed in medians with quartile 1 to quartile 3 in square brackets or alternatively in numbers with percentages in parentheses.
a
Calculated by the CKD-EPI 2009 equation.
b
At the time of Ca2s+ determination.