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. 2015 Dec 7;25(3):219–226. doi: 10.1159/000443145

Table 3.

Reliability and accuracy for the predictive equations

ICC ME, mmol/dl MAPE, s% MAE, mmol/dl RMSE, mmol/dl
All patients
Equation 1 0.539 (0.373 to 0.663) −0.04 (−0.05 to −0.02) 7.35 (6.17 to 8.53) 0.08 (0.07 to 0.09) 0.04 (0.03 to 0.06)
Equation 2 0.609 (0.480 to 0.709) −0.03 (−0.04 to −0.01) 6.51 (5.43 to 7.59) 0.07 (0.06 to 0.08) 0.03 (0.02 to 0.05)
Equation 3 0.521 (0.347 to 0.651) −0.04 (−0.06 to −0.02) 7.30 (6.10 to 8.50) 0.08 (0.07 to 0.09) 0.04 (0.03 to 0.06)

Published general predictive equations
McLean-Hastings 0.345 (−0.095 to 0.675) −0.24 (−0.26 to −0.22) 21.72 (19.95 to 23.48) 0.24 (0.22 to 0.26) 0.30 (0.25 to 0.34)
Zeisler 0.496 (−0.070 to 0.766) 0.11 (0.10 to 0.13) 10.64 (9.61 to 11.68) 0.12 (0.11 to 0.13) 0.08 (0.07 to 0.10)
Zeisler simplified 0.506 (−0.051 to 0.766) 0.11 (0.09 to 0.12) 10.37 (9.33 to 11.41) 0.12 (0.11 to 0.13) 0.08 (0.07 to 0.10)
Hanna 0.264 (0.050 to 0.621) −0.26 (−0.27 to −0.25) 23.65 (22.15 to 25.16) 0.26 (0.25 to 0.27) 0.30 (0.27 to 0.33)
Pottgen 0.508 (0.174 to 0.699) −0.08 (−0.10 to −0.06) 9.67 (8.29 to 11.04) 0.11 (0.09 to 0.12) 0.08 (0.05 to 0.10)
Siggaard-Andersen 0.731 (0.646 to 0.799) −0.01 (−0.03 to 0.01) 8.04 (7.04 to 9.04) 0.09 (0.08 to 0.10) 0.05 (0.04 to 0.06)
Butler 0.095 (−0.063 to 0.251) 0.02 (0 to 0.04) 8.48 (6.89 to 10.07) 0.09 (0.08 to 0.11) 0.06 (0.04 to 0.09)
Special populations
Critically ill patientsa
 Equation 1 0.556 (0.054 to 0.844) −0.04 (−0.08 to 0) 6.20 (3.91 to 8.50) 0.07 (0.04 to 0.09) 0.02 (0.01 to 0.04)
 Equation 2 0.640 (0.16 to 0.879) −0.03 (−0.07 to 0) 5.21 (2.79 to 7.63) 0.06 (0.03 to 0.08) 0.02 (0 to 0.04)
 Equation 3 0.528 (−0.015 to 0.835) −0.05 (−0.09 to −0.01) 6.44 (3.83 to 9.05) 0.07 (0.04 to 0.09) 0.03 (0.01 to 0.04)
 Forster 0.623 (0.113 to 0.874) −0.02 (−0.07 to 0.03) 8.73 (4.74 to 12.72) 0.07 (0.04 to 0.10) 0.03 (0.01 to 0.05)
Patients ≥80 years oldb
 Equation 1 0.417 (0.008 to 0.699) −0.06 (−0.08 to −0.03) 7.36 (5.43 to 9.30) 0.08 (0.06 to 0.10) 0.03 (0.02 to 0.05)
 Equation 2 0.494 (0.108 to 0.743) −0.04 (−0.07 to −0.02) 6.48 (4.75 to 8.21) 0.07 (0.05 to 0.08) 0.03 (0.01 to 0.04)
 Equation 3 0.390 (−0.054 to 0.695) −0.07 (−0.09 to −0.04) 7.81 (5.82 to 9.80) 0.08 (0.06 to 0.10) 0.04 (0.02 to 0.05)
 Pfitzenmeyer 0.441 (−0.095 to 0.759) −0.08 (−0.10 to −0.06) 5.94 (4.47 to 7.40) 0.09 (0.07 to 0.11) 0.04 (0.03 to 0.05)

ICC = Intraclass concordance coefficient, values of s+1 denote perfect concordance and 0 denotes absence of concordance; ME = mean error; MAPE = mean absolute percentage error; MAE = mean absolute error; RMSE = root mean square error, in all cases lower is better. 95s% CIs are given in parentheses.

a

For 12 (8.2s%) critically ill patients.

b

For 26 (17.8s%) patients ≥80 years old.