Table 1.
Eself1 | Epartner1 | Epartner2 | Eself2 | |
---|---|---|---|---|
E1-E2 (Fig. 2) | ||||
Control, n = 25 | 3.84 ± 0.71 | 2.28 ± 0.52 | 2.47 ± 0.43 | 3.32 ± 0.68 |
Mutant, n = 27 | 4.37 ± 0.73 | 2.21 ± 0.64 | 4.43 ± 0.67 | 7.49 ± 1.41 |
p | 0.637 | 0.353 | 0.016 | 0.008 |
I-E (Fig. 3) | Iself | Ipartner | Epartner | Eself |
Control, n = 20 | 4.05 ± 0.69 | 1.72 ± 0.24 | 7.91 ± 1.48 | 3.37 ± 0.997 |
Mutant, n = 23 | 8.84 ± 1.54 | 2.08 ± 0.33 | 16.48 ± 2.51 | 8.12 ± 1.71 |
p | 0.029 | 0.436 | 0.005 | 0.044 |
I1-I2 (Fig. 4) | Iself1 | Ipartner1 | Ipartner2 | Iself2 |
Control, n = 20 | 5.21 ± 1.25 | 2.49 ± 0.65 | 2.58 ± 0.56 | 5.22 ± 1.49 |
Mutant, n = 20 | 5.33 ± 0.85 | 2.97 ± 0.77 | 4.54 ± 0.80 | 13.92 ± 2.07 |
p | 0.414 | 0.705 | 0.033 | 0.002 |
E-I (Fig. 5) | Eself | Epartner | Ipartner | Iself |
Control, n = 21 | 3.10 ± 0.97 | 8.71 ± 1.35 | 2.28 ± 0.32 | 4.42 ± 0.69 |
Mutant, n = 18 | 2.35 ± 0.70 | 4.74 ± 0.81 | 4.81 ± 0.73 | 9.92 ± 2.01 |
p | 0.278 | 0.024 | 0.007 | 0.014 |
aData are mean ± SEM of the peak synaptic current (nA) in response to a 2 ms depolarization to 0 mV delivered at 0.1–0.2 Hz. Measurements in the first column correspond to green traces, second column to blue traces, third column to gray traces, and fourth column to orange traces in Figures 2–5. p values were obtained from Mann–Whitney tests.