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. 2017 Sep 6;37(36):8797–8815. doi: 10.1523/JNEUROSCI.0338-17.2017

Figure 4.

Figure 4.

The behavioral defects associated with unc-13 mutant animals are partially rescued by the expression of the P334A mutant UNC-18. A, Expression of mutant UNC-18 in the unc-13 and unc-18 double loss-of-function mutant background partially restores motility measured by thrashing assays. In a one-way ANOVA statistical test, mutant UNC-18 was excluded: F(2,69) = 8.9, p = 3.74E-4. n = 19–28. B, Expression of mutant UNC-18 in the unc-13 and unc-18 double mutant background partially restores locomotion speed measured in the presence of food. n = 15–16. In a one-way ANOVA statistical test, F(2,43) = 6.3 and p = 0.004. *p < 0.05. Tukey's test was performed for means comparisons in ANOVA. Error bars indicate SEM.