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. 2017 Jul 24;190(1):19–28. doi: 10.1111/cei.13004

Figure 2.

Figure 2

Vaccination with wild‐type nucleoprotein (NPwt) protein with Matrix‐M™ adjuvant or recombinant Modified Vaccinia virus Ankara (rMVA)–NPwt induced NP‐specific splenocyte responses. Spleens obtained 14 days after the booster vaccination were stimulated with purified NPwt protein. The number of interleukin (IL‐)2 (a), interferon (IFN‐)γ (b) and IL‐2/IFN‐γ (c)‐producing T cells was used to determine NP‐specific splenocyte activation in spot‐forming units (SFU)/106 cells. Samples were tested in triplicate. Mean of each group is indicated. MM = Matrix‐M™ adjuvant. *P < 0·0306; **P < 0·0082; ***P = 0·0005.