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. 2017 Jul 24;190(1):19–28. doi: 10.1111/cei.13004

Figure 3.

Figure 3

Nucleoprotein (NP)‐specific antibody responses induced by vaccination with NP wild‐type (NPwt) protein + Matrix‐MTM adjuvant or the respective recombinant Modified Vaccinia virus Ankara (rMVA)–NP constructs. Immunoglobulin (Ig)G1 and IgG2a NP‐specific antibody responses in mice 21 days after the primary vaccination (a,b) or 14 days after booster vaccination (c,d). IgG1 (a,c) or IgG2a (b,d) serum antibodies were detected using purified NPwt protein and anti‐IgG1 or anti‐IgG2a horseradish peroxidase (HRP)‐conjugated antibodies. Mean for each group is indicated. MM = Matrix‐M™ adjuvant. *P < 0·0432; **P < 0·0068; ***P < 0·0009; ****P < 0·0001.