Table 2.
Correlations with haemoglobin A1c (HbA1c), C‐peptide, nitric oxide (NO), C‐reactive protein (CRP), C3d and sC5b–9 in the type 1 diabetes (T1D)‐enterovirus (EV)– groups
| HbA1c | C‐ peptide | NO | CRP | C3d | sC5b–9 | |
|---|---|---|---|---|---|---|
| r (P‐value) | ||||||
| GADA | 0·02 (0·849) | 0·04 (0·695) | 0·2 (0·05) | −0·2 (0·09) | −0·2 (0·4) | −0·07 (0·783) |
| IAA | −0·14 (0·175) | 0·16 (0·114) | 0·1 (0·336) | −0·07 (0·05) | −0·37 (0·121) | 0·115 (0·65) |
| ICA | 0·10 (0·318) | 0·13 (0·181) | −0·08 (0·382) | 0·007 (0·93) | −0·23 (0·359) | 0·453 (0·04) * |
| IFN‐γ | −0·12 (0·254) | −0·05 (0·6) | −0·07 (0·485) | −0·06 (0·54) | 0·06 (0·81) | −0·2 (0·422) |
| TNF‐α | 0·11 (0·269) | −0·11 (0·27) | 0·12 (0·233) | 0·077 (0·44) | −0·006 (0·98) | −0·15 (0·546) |
| IL‐1β | −0·02 (0·881) | −0·08 (0·43) | −0·13 (0·2) | 0·122 (0·225) | 0·11 (0·657) | 0·3 (0·2) |
| IL‐12 | 0·11 (0·287) | 0·04 (0·7) | −0·03 (0·76) | 0·154 (0·126) | 0·017 (0·94) | −0·173 (0·5) |
| IL‐4 | 0·06 (0·535) | −0·16 (0·11) | −0·04 (0·68) | −0·026 (0·8) | −0·48 (0·05) | 0·27 (0·27) |
| IL‐6 | 0·02 (0·808) | 0·02 (0·876) | −0·04 (0·6) | 0·05 (0·6) | 0·063 (0·8) | −0·13 (0·6) |
| IL‐13 | −0·14 (0·160) | −0·17 (0·1) | −0·09 (0·366) | −0·12 (0·22) | −0·6 (0·01) * | 0·1 (0·7) |
| IL‐20 | −0·33 (0·001) ** | −0·10 (0·326) | −0·04 (0·7) | −0·06 (0·55) | −0·04 (0·86) | 0·23 (0·35) |
| IL‐10 | −0·20 (0·05) | −0·08 (0·408) | −0·05 (0·6) | 0·06 (0·55) | 0·28 (0·25) | 0·28 (0·25) |
| IL‐17 | 0·14 (0·150) | 0·10 (0·303) | 0·1 (0·24) | 0·035 (0·72) | 0·136 (0·58) | −0·5 (0·03) * |
| TGF‐β | −0·04 (0·7) | −0·015 (0·87) | −0·07 (0·46) | 0·07 (0·44) | −0·3 (0·21) | 0·08 (0·7) |
GADA = glutamic acid decarboxylase; IAA = insulin autoantibodies; ICA = islet cell cytoplasmic autoantibodies; IFN = interferon; TNF = tumour necrosis factor; IL = interleukin; TGF = transforming growth factor. *P < 0·05; **P < 0·01.