Table 4.

Relationship between the presence of cortical, cerebellar, and subcortical infarcts and incident dementia

	Infarcts vs. no infarcts
Infarct region/infarct groups:	Incident dementia (n=358)	Without dementia (n=2254)	Risk-ratio (95%CI)
Cortical
No prevalent & no incident	267	1928	Reference
One or more prevalent & no incident	39	175	1.3 (1.0–1.7)
No prevalent & one or more incident	32	97	1.7 (1.3–2.2)
One or more prevalent & one or more incident	20	54	1.5 (1.00–2.2)
Cerebellar
No prevalent & no incident	234	1643	Reference
One or more prevalent & no incident	50	345	0.9 (0.7–1.2)
No prevalent & one or more incident	39	155	1.2 (0.9–1.6)
One or more prevalent & one or more incident	35	111	1.5 (1.1–2.1)
Subcortical
No prevalent & no incident	290	2050	Reference
One or more prevalent & no incident	27	129	1.2 (0.8–1.6)
No prevalent & one or more incident	32	48	2.6 (1.9–3.4)
One or more prevalent & one or more incident	9	27	1.9 (1.1–3.3)

Values show number of subjects with infarcts in the various regions versus those with no infarcts in corresponding regions in the groups of subjects with and without incident dementia together with the risk-ratios of incident dementia by infarct group. Risk-ratios are with 95% confidence intervals (95%CI) adjusted for baseline age, sex, time interval between MRI scans.