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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Transfusion. 2016 Sep 9;56(12):3047–3054. doi: 10.1111/trf.13801

Figure 1. Genetic variations in the ERMAP gene.

Figure 1

The ERMAP gene is located at chromosome 1p34.2 and consists of 12 exons encoding a protein of 475 amino acids. The exons (▯) are shown schematically along with their 5′-UTR, 3′-UTR and 11 introns (——). The primary 21,406 nucleotide amplicon covered the complete 1,428 nucleotide coding sequence (CDS) in the exons 3 to 12. It also encompassed 1,941 bp of intron 1, 116 bp of the non-coding exon 2, 1,757 bp of the 3′-UTR and 16,066 bp of the introns 2 to 11. The positions of the 80 variations (SNPs) are indicated (│) in the exons (red) and introns (green). The 7 additional SNPs in the exons indicative for the Scianna phenotypes SC:1, SC:2, SC:-3, SC:4, SC:-5, SC:-6 and SC:-7 were not observed in this study (blue).