| Inclusion criteria for nipple-sparing mastectomy study: |
| 1. Unilateral or bilateral prophylactic mastectomy |
| 2. Ipsilateral breast cancer patients not meeting exclusion criteria detailed below |
| 3. Appropriate reconstructive surgery candidate |
| 4. Patient undergoing immediate breast reconstruction |
| Absolute exclusion criteria for nipple sparing mastectomy study: |
| 1. Direct nipple involvement with tumor on permanent pathologic exam of a biopsy taken from the remaining major duct on retroareolar complex |
| 2. Large tumor size (T3 or greater) |
| 3. Patient not undergoing immediate reconstruction |
| Relative exclusion criteria for study participation: |
| 1. Extensive DCIS or microcalcifications (as determined by mammogram, US or MRI) |
| 2. Poor reconstructive candidate (as determined by plastic surgeon) |
| 3. Tumors with characteristics not meeting the above inclusion criteria |
