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Prominent neural progenitor/glial cell presence 7 days post injection. Nestin+ staining (red) in and surrounding the injection site was observed for all groups at day 7 (A-D). Little to no co-localization of nestin with CXCR4+ cells (green) was noted at day 7 for any of the conditions, Vehicle (A, a), blank NPs (B, b), SDF-1 bolus (C, c), and AFSDF-1 NP (D, d). Red = nestin, Green = CXCR4, Blue = DAPI. (A-D) Scale bar = 100 μm; (a-d) scale bar = 20 μm.
