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Pronounced astrocytic response following intracortical injections. (A-D) Representative day 7 images demonstrated pronounced GFAP response adjacent to the inject tract for all groups with little to no co-localization with CXCR4 (a-d). (A, a) Vehicle, (B, b) Blank NPs, (C, c) SDF-1bolus, and (D, d) SDF-1 NPs. Red = GFAP, Green = CXCR4, Blue = DAPI. (A-D) Scale bar = 200 μm, (a-d) scale bar = 20 μm.
