Skip to main content
. Author manuscript; available in PMC: 2018 Jul 25.
Published in final edited form as: Biomater Sci. 2017 Jul 25;5(8):1640–1651. doi: 10.1039/c7bm00489c

Figure 5.

Figure 5

AFSDF-1 NPs enable sustained SDF-1 delivery. (A) Total SDF-1 (endogenous + exogenous) immunopostitive staining for days 1, 3, and 7 after injection. Only the SDF-1 NPs demonstrated significantly higher percent positive area compared to all groups at day 1 and 3 (A; #p < 0.01) and the vehicle control at day 7 (A; *p < 0.05). (B-D) Spatial distribution of the SDF-1 immunostain relative to the injection site over days 1, 3, and 7. SDF-1 NPs displayed significantly higher percent area of immunostain within 400 μm of the injection compared to all groups at all days (B-D; #p < 0.01). SDF-1 bolus was significantly higher than vehicle control and blank NPs at day 1 (B; #p < 0.01) and only vehicle control at day 3 (C; $p < 0.05). Box whisker plots used in B-D to demonstrate the span of data points within each group; n = 4-5 animals per group.