Table 1.
Published markers for cardiac fibroblasts.
| Method of Detection | E12.5 | E14.5 – E18.5 | Adult | Injury Phase | Reference(s) | ||
|---|---|---|---|---|---|---|---|
| Nuclear | WT1 | GT, IHC | Ep, CM | Ep, EC, CM | Ep, ECLow | Ep, P/V, EC | 18, 31, 114, 115, 118 |
| Tcf21 | GT, IHC | Ep | F, Ep | F, Ep | F, Ep | 7, 19, 33, 53, 54, 116 | |
| Cytosollic | FSP1 | GT, IHC | NE | F*, P/V | F*, P/V, EC, IC | F*, P/V, IC, EC | 7, 117, 26, 44, 53, 118 |
| Prolyl-4-hydroxylase | IHC | F, EC | F, IC | 26, 107, 117, 119 | |||
| Cytoskeletal | Vimentin | IHC | En | F, P/V | F, P/V, EC | F, P/V | 7, 21, 33, 53, 117, 120, 121 |
| αSMA | GT, IHC | Ep, CM | P/V, CM | P/V | F*, P/V | 26, 33, 53, 118, 122 | |
| Cell membrane | PDGFRα | GT, IHC | Ep | F | F, CPC | F | 21, 26, 33, 40, 53, 105, 123, 124 |
| MEFSK4 | FC | F, P/VLow, IC | F, P/VLow, IC | 40 | |||
| DDR2 | FC, IHC | Ep | F*, P/V, En | F, P/V | F, P/V | 7, 41, 43, 53, 124–127 | |
| CD90 | FC, IHC | F*, P/V, IC, EC | F*, P/V, IC, EC | F*, P/V, IC, EC | 40, 42, 53, 118, 121, 128 | ||
| Sca1 | FC, GT, IHC | NE | F*, CPC | F*, CPC | 40, 45, 105, 129, 130 | ||
| Extracellular | Periostin | GT, IHC | Ep | F, P/V | NE | F* | 7, 33, 41, 44, 53, 70, 117 |
| Fibronectin | IHC | F, EC | F, EC | F* | 7, 33, 46, 118 | ||
| ED-A fibronectin | IHC | NE | NE | F*, EC | 117, 131, 132 | ||
| Collagen type I | GT, IHC | Ep | F, P/V | F, P/V | F, EC, CM | 7, 21, 33, 41, 53, 58, 70 | |
| Collagen type III | IHC | F, P/V | F, P/V | F, P/V | 7, 41, 133 | ||
| FAP | FC, IHC | F | 51, 117 | ||||