Table 2.

Guide Sequences Tested

Guide	Sequence	PAM	Locus	Figure
sg1MAK	GATAGTAGCTTGTGCATGAA	AGG	chr6:+10792160	Figure 1
sg2MAK	TATGGAACGCTCCTTGAGAA	TGG	chr6:+10792116	Figure 1
sg3MAK	ACTAACAGTCCCCATTCTCA	AGG	chr6:−10792116	Figure 1
sg1CEP290	TATCTCATACCTATCCCTAT	TGG	chr12:-88102776	Figure 2
sg2CEP290	GAGATACTCACAATTACAAC	TGG	chr12:+88102748	Figure 2
sg3CEP290	TTAACGTTATCATTTTCCCA	AAGAGT	chr12:−88102763	Figure 3
sg4CEP290	GTTTCATTCTGTCACCCAGG	CTGGAT	chr12:−88102837	Figure 3
sg5CEP290	GTAAGACTGGAGATAGAGAC	AGGAAT	chr12:+88101105	Figure 3
sg6CEP290	TTTTGACAGTTTTTAAGGCG	GGGAGT	chr12:+88101195	Figure 3
sgH23-1	GACGGGTGTGGTACGCAGCCACT	TCGAGT	chr3:+129528801	Figure 4
sgH23-2	GGGTGTGGTACGCAGCCACT	TCGAGT	chr3:+129528801	Figure 4