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| Nav subtype | Cd1a (IC50, μM)* |
Cm1a (IC50, μM) |
Cm1b (IC50, μM) |
|---|---|---|---|
| Nav1.1 | 2.18 ± 0.69 | 1.06 ± 0.32 | 0.17 ± 0.11 |
| Nav1.2 | 0.13 ± 0.04 | 0.07 ± 0.22 | 0.08 ± 0.02 |
| Nav1.3 | > 30 | > 10 | 5.57 ± 0.04 |
| Nav1.4 | > 30 | > 10 | > 10 |
| Nav1.5 | > 30 | > 10 | > 10 |
| Nav1.6 | > 30 | > 10 | 3.99 ± 1.60 |
| Nav1.7 | 3.34 ± 1.56 | 5.12 ± 2.85 | 0.23 ± 0.13 |
| Nav1.8 | 6.92 ± 3.44 | > 10 | > 10 |
*Data are expressed as mean ± SEM.
